Povara alostatică şi consecințele sale asupra organismului

Abstract

The concept of alostasis, or “stability through change”, has been proposed as an amendment to the homeostatic model. The brain controls both the physiologic and the behavioral coping responses to daily events as well as major stressors, and the nervous system is itself a target of the mediators of that response through circulating hormones. Alostatic load leads to bone demineralization, obesity impaired immunity.