Infecţiile urinare cu enterobacteriaceae dificultăţi terapeutice

Abstract

The aim of this retrospective study has consisted in analysing the resistance to antibiotics of the germs from the Enterobacteriaceae family implicated in urinary infections. The study group has consisted in the patients hospitalized in the Clinical County Emergency Hospital of Braşov during a 2 years period (2007-2008). From the urine of these patients there were isolated 3281 Enterobacteriaceae strains. The preparation of the urine samples for the bacteriologic diagnosis has been performed in the laboratory of this medical unit, according to standard methodologies. The identification was based on biochemical methods and the testing of susceptibility to antibiotics of the germs ethiologically implicated was performed using the standardized Kirby-Bauer method and the automated VITEK 2 COMPACT system. The ethiological spectrum of urinary tract infections was dominated by Escherichia coli species (77.7%), followed, with lower percenteges, by Enterobacter spp., Proteus spp., Klebsiella spp. şi Citrobacter spp. All the isolated Enterobacteriaceae strains have presented different levels of resistance to antibiotics, with the exception of colistine, for which the sensitivity in vitro was preserved. The sensitivity to imipenem was higher in all the analyzed bacterial genres.