Evoluţia Consimţământului Informat în cercetarea clinică | [Evolution of Informed consent in clinical research]

Abstract

Informed consent in clinical research is the documented expression of freely, advisedly given will of patients to participate in a certain clinical trial. The development of informed consent regulations in clinical research was based upon the legal actions taken by patients against their physicians, which forced the authorities to elaborate ethical codes and guidelines regarding the protection of human subjects' rights and welfare. This article describes when and how the principles of research on human subjects appeared and developed, from their origins, to present times.