Noi markeri pentru diagnosticul non-invaziv în endometrioză | [New markers for the non-invasive diagnosis of endometriosis]

Abstract

Endometriosis represents one of the most frequent benign gynecological diseases caused by pelvic pain and infertility. The pathogenesis is related to the peritoneal implants of endometrial fragments which are generating local inflammation, and cytokine production by peritoneal T and B cells, macrophages, astrocytes, and epithelial and mesothelial cells, on the background of an altered immune response. Even the laparoscopy is the main diagnostic tool, some series markers (IL-6, TNF-α, hs-CRP) could be used for the diagnosis and the severity assessment of this condition.