Neuropatia diabetică autonomă cardiovasculară, din teorie in practica clinică | [Cardiovascular autonomic diabetic neuropathy, from theory to clinical practice]

Abstract

Cardiac autonomic neuropathy (CAN) is one of the most common complications of diabetes mellitus. CAN is recognized as a strong independent predictor for cardiac events, it increases both mortality and morbidity risk in diabetic patients. The imbalance between the sympathetic and parasympathetic nervous systems due to impaired autonomic function is leading to an increased arrhythmic risk. Heart rate variability (HRV) reflects the cardiac autonomic function and a reduced HRV in diabetic patients reflects a sympathetic dominance. In clinical practice, HRV measurements are obtained with an analysis of RR fluctuations in continuous ECG monitoring. HRV indexes are analyzed in time and frequency domains. Further research is required to standardize HRV indexes by gender and age.