Sindromul cardiorenal – o scurtă evaluare pe baza literaturii de specialitate | [Cardiorenal syndrome - a short review based on current understanding]

Abstract

Maintenance of blood volume, vascular tone, and hemodynamic stability depends on a set of elegant interactions between the heart and kidney. For some time, physicians have recognized that severe dysfunction in either of these organs seldom occurs in isolation. However, only recently have we attempted to define and apply the widespread concept of cardio-renal syndrome (CRS). Despite our growing use of the term, there is still some debate as to its true definition. More important, the process itself remains enigmatic; our understanding of the complex physiological, biochemical, and hormonal derangements that encompass the CRS is woefully deficient and may lead to improper medical management of patients.