Rolul cistatinei C versus creatinina ca marker endogen al funcției renale | [The role of cystatin C versus endogenous creatinine as markers of renal function]

Abstract

Kidney function estimates are central to the diagnosis and management of chronic kidney disease, and these estimates are usually based on the creatinine blood test. However, the creatinine test can miss early losses of kidney function, particularly in patients with low muscle mass. Cystatin C, a newer kidney function marker, is becoming more widely available and in some settings provides improved estimates of kidney function. Cystatin C defines an important preclinical period of reduced kidney function before chronic kidney disease can be diagnosed with creatinine alone.