Cytotoxic Potential of Industrial Hemp Extracts

Authors

  • A. Grigore National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania
  • L. Pirvu National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania
  • C. Bubueanu National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania
  • I. Tabrea National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania
  • M. Petrescu National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania
  • I. Bejanaru National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

DOI:

https://doi.org/10.31926/but.fwiafe.2021.14.63.2.10

Keywords:

Cannabis sativa, cancer, polyphenols

Abstract

Industrial hemp (Cannabis sativa L.) is a source of fibers, oil, and valuable secondary metabolites. Regarding phenolic compounds, it has to be noted that the plant biosynthesizes molecules with various pharmacological benefits. The aim of this study was to prove the cytotoxic potential of hemp polar and non-polar fractions against two cancer cell lines (BT-20 and U87). The study revealed the potential antitumor activity of industrial hemp selective fractions but a correlation between polyphenols content and the cytotoxic effect could not be established.

Author Biographies

A. Grigore, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Pharmaceutical Biotechnologies Department, Calea Vitan, no. 112

L. Pirvu, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Pharmaceutical Biotechnologies Department, Calea Vitan, no. 112

C. Bubueanu, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Pharmaceutical Biotechnologies Department, Calea Vitan, no. 112

I. Tabrea, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Pharmaceutical Biotechnologies Department, Calea Vitan, no. 112, 

M. Petrescu, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Pharmaceutical Biotechnologies Department, Calea Vitan, no. 112

I. Bejanaru, National Institute of Chemical-Pharmaceutical Research and Development, Bucharest, Romania

Analytical Department, Calea Vitan, no. 112

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Published

2021-12-22

Issue

Vol. 14(63) No. 2 (2021)

Section

AGRICULTURAL FOOD ENGINEERING