https://webbut.unitbv.ro/index.php/Series_VI <h2>Aim</h2> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify;"><span style="font-size: 10.5pt; font-family: 'Segoe UI','sans-serif';">This is a medical multidisciplinary journal publishing original research papers, and case presentations.</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify;"><span style="font-size: 10.5pt; font-family: 'Segoe UI','sans-serif';">The yearly journal presents the latest results in medical research, focusing on integrated, interdisciplinary approaches. Also, it is committed to publishing work on different fields of the health profession and the history of medicine.</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify;"><span style="font-size: 10.5pt; font-family: 'Segoe UI','sans-serif';">The aim of the journal is to promote excellence and is open to research groups all over the world and mostly welcomes scientific papers from groups involving young researchers.</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: justify;"><span style="font-size: 10.5pt; font-family: 'Segoe UI','sans-serif';">The Journal is indexed in EBSCO Publishing DataBase (<a href="http://webbut.unitbv.ro/public/site/documents/admin/a9h-subject.xls">http://www.ebscohost.com/titleLists/a9h-subject.xls</a>), from 2010, ProQuest Central (<a href="https://search.proquest.com/central/" target="_blank" rel="noopener">https://search.proquest.com/central/</a>), from 2008, and in Crossref (<a href="https://search.crossref.org" target="_blank" rel="noopener">https://search.crossref.org</a>), from January 2019.</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: right;" align="right"> </p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: right;" align="right"><span style="font-family: 'Segoe UI','sans-serif';">Senior-editor,</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: right;" align="right"><span style="font-family: 'Segoe UI','sans-serif';">Marius IRIMIE</span></p> <p style="margin: 0cm; margin-bottom: .0001pt; text-align: right;" align="right"><span style="font-family: 'Segoe UI','sans-serif';"><a href="http://webbut.unitbv.ro/index.php/Series_VI/about" target="_blank" rel="noopener">Read more</a></span></p> Transilvania University Press en-US Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences 2065-2216 https://webbut.unitbv.ro/index.php/Series_VI/article/view/11836 Intrahepatic cholestasis of pregnancy (ICP) is the most common pregnancy-specific liver disease, characterized by pruritus associated with elevated serum bile acid concentrations and abnormal liver function tests in the absence of another obvious etiology. Although maternal symptoms are, in most cases, self-limited and resolve rapidly after delivery, clinical and scientific interest in this entity derives from its disproportionate impact on fetal prognosis, making ICP a condition of major clinical relevance in maternal-fetal medicine: PubMed, Embase, and Cochrane Library, complemented by an additional literature exploration through Google Scholar to identify relevant articles that were not indexed in a standard way The methodological quality of the included studies was assessed by evaluating study design, sample size, inclusion criteria, and potential sources of bias, including selection, confounding, and reporting bias. Maternal disease severity may appear disproportionate to the potential fetal consequences, making clinical management complex and highly individualized. Conclusion. This review highlights the current evidence linking ICP to adverse perinatal outcomes, with important implications for risk stratification and clinical management practice. D.A. Meret L.M. Rogozea M. Irimie M.A. Moga M.A. Dinuta-Smeu A. Prahoveanu Copyright (c) 2026 Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences 2026-08-25 2026-08-25