Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences

https://webbut.unitbv.ro/index.php/Series_VI/issue/feed Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences 2025-05-15T09:08:41+00:00 Prof. Dr. MD Alina PASCU editor.but@unitbv.ro Open Journal Systems <h2>Aim</h2> This is a medical multidisciplinary journal publishing original research papers, and case presentations. The yearly journal presents the latest results in medical research, focusing on integrated, interdisciplinary approaches. Also, it is committed to publishing work on different fields of the health profession and the history of medicine. The aim of the journal is to promote excellence and is open to research groups all over the world and mostly welcomes scientific papers from groups involving young researchers. The Journal is indexed in EBSCO Publishing DataBase (<a href="http://webbut.unitbv.ro/public/site/documents/admin/a9h-subject.xls">http://www.ebscohost.com/titleLists/a9h-subject.xls</a>), from 2010, ProQuest Central (<a href="https://search.proquest.com/central/" target="_blank" rel="noopener">https://search.proquest.com/central/</a>), from 2008, and in Crossref (<a href="https://search.crossref.org" target="_blank" rel="noopener">https://search.crossref.org</a>), from January 2019. <a href="http://webbut.unitbv.ro/index.php/Series_VI/about" target="_blank" rel="noopener">Read more</a> https://webbut.unitbv.ro/index.php/Series_VI/article/view/9002 Dermatofibrosarcoma Protuberans, a Challenging Entity – Case Report and Brief Literature Review 2025-02-12T07:13:07+00:00 A.C. Tinca tinca1@yahoo.com B.A. Lazar lazar1@yahoo.com E.S. Negovan negovan1@yahoo.com O.S. Cotoi cotoi1@yahoo.com

Dermatofibrosarcoma protuberans (DFSP) is a rare, locally aggressive soft tissue tumour of mesenchymal origin, commonly arising in the dermis and extending into deeper tissues. This article presents a case of a 52-year-old male with recurrent DFSP affecting the posterior neck region. Initial surgical excision in 2016 revealed a spindle-cell tumour with storiform patterns and a low mitotic index, while recurrence in 2022 exhibited a multinodular, infiltrative mass with increased cellular atypia and a high mitotic rate. Immunohistochemistry confirmed diffuse CD34 positivity in both instances. Complete surgical excision, including re-excision for margin involvement, achieved tumour-free status. The case highlights the importance of histological evaluation, surgical approach and follow-up in these cases. Long-term monitoring remains essential due to DFSP’s high recurrence potential.

2025-01-12T00:00:00+00:00 Copyright (c) 2025 Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences https://webbut.unitbv.ro/index.php/Series_VI/article/view/10109 Perioperative Analgesic Strategies for Long Bone Fractures. Is There a Need for a Standardized Protocol? A Scoping Review 2025-05-15T08:33:30+00:00 M.S. Moldovan moldovan1@yahoo.com A. Mironescu aurel.mironescu@unitbv.ro

Acute perioperative pain that accompanies limb fractures and exceeds the threshold of tolerability has a high risk of becoming chronic. There are many controversies regarding current pain management options, like opioids and nonsteroidal anti-inflammatory drugs. This study aimed to comprehensively search the literature for ways to achieve perioperative analgesia in patients with long bone fractures. This research was a scoping review that included a systematic search of randomized controlled trials and observational studies in three international databases: MEDLINE, Scopus, and Web of Science. Ten thousand nine hundred forty-three articles were found and screened. After applying the inclusion and exclusion criteria, 77 articles were included in the final descriptive analysis. Peripheral nerve blocks play a significant role in perioperative multimodal analgesia; of the articles described in this review, 46.75% revolved around regional anesthesia. Other findings of pharmacologic agents that are of benefit in improving pain scores in surgically treated long bone fractures and need future research are Gabapentinoids, Magnesium sulphate, Vitamin C, Esmolol, and low-dose Ketamine.

2025-05-15T00:00:00+00:00 Copyright (c) 2025 Bulletin of the Transilvania University of Brasov. Series VI: Medical Sciences https://webbut.unitbv.ro/index.php/Series_VI/article/view/10110 Pharmacists and Community-Based Pharmacies in an Expanded Role in Patient Care and Public Health in The U.S. 2025-05-15T08:46:16+00:00 Darrell Norman Burrell burrell1@yahoo.com

The COVID-19 pandemic catalyzed the rapid integration of telehealth and digital health technologies, presenting both transformative opportunities and profound challenges in healthcare delivery. While these innovations promise to enhance access to care, they have also exposed and, in some instances, exacerbated existing health disparities. In response to these challenges, pharmacists have the potential to function in expanded roles as frontline healthcare providers, transitioning from traditional medication dispensers to key public health leaders. Community-based pharmacies emerged as critical hubs for vaccination campaigns, telepharmacy services, and chronic disease management, offering culturally responsive care in accessible spaces. This perspective paper explores the evolving role of pharmacists and community pharmacies in addressing health disparities through innovative care models that integrate digital health solutions and community-based outreach in roles as primary care pharmacists, health educators, recruiters for clinical trials, and facilitators for telehealth visits. By leveraging their trusted relationships within communities, pharmacists are uniquely positioned to promote digital literacy, increase diverse patient engagement in clinical trials, and advocate for culturally tailored care strategies. The paper underscores the ethical imperative of ensuring digital health equity while offering practical solutions for bridging the digital divide. It advocates for a reimagined pharmacy model that prioritizes access, equity, and innovation, positioning pharmacists and community pharmacies as pivotal change agents in building a more inclusive and just healthcare system. Through this inquiry, the paper calls on policymakers and healthcare leaders to adopt community pharmacy and pharmacist-driven strategies that advance health equity for all populations.