Biocompatibility and Physical Properties of Doped Bioactive Glass Ceramics

Abstract

Biocompatibility of a new bioactive glass composition for medical applications was evaluated with the addition of fluorides, such as CaF2 and MgF2, for the substitution of Na2O in the conventional bioactive glass composition (SiO2-CaO-Na2O-P2O5). Also, the physical properties of these glass-ceramics were investigated. When B2O3 was added as a Na2O substitution, the thermal expansion coefficient was decreased in sintered samples. Compared to the low flexural strength and Vickers hardness of sintered bioactive glass ceramics without fluoride and B2O3 additions, new bioactive glass ceramics substituted with 10 mol% MgF2 for Na2O showed higher mechanical properties.