The Spectrum of Infections and the Resistance to Antibiotics of Enterobacter Species

Abstract

The study was retrospective and included 112 Enterobacter strains isolated from the prelevates of the patients hospitalized in the Clinical County Emergency Hospital Braşov for 6 months (1.01.2010-31.06.2010). The aims of our study were to analyze the spectrum of infections caused by Enterobacter spp. and the assessment of the resistant strains isolated from the prelevates of the hospitalized patients. The etiological spectrum of infections produced by Enterobacter species was large, these germs being most frequently implicated in urinary tract infections (48%) and wound infections (27%). The resistance of Enterobacter spp. to beta-lactams was high, especially to ampicillin (94,92%). The level of resistance to quinolones was relatively high, but the role of these antibiotics is still important in the therapy of Enterobacter spp. infections. The resistance to aminoglycosides was different, being higher in the case of gentamicin (51,56%). The sensitivity of Enterobacter spp. to carbapenems and colistin was very high, these antibiotics represented the therapeutical solution even in infections produced by Enterobacter ESBL-producing strains. The selection of resistant strains for these antibiotics is however worrying. The obtained results sustain the need to implement coherent strategies for the monitoring of the occurrence and spread of the resistance phenomenon.