Penile Paraffinomas after Self-Injection with Kanamicim Ointment

Abstract

Introduction: Penile paraffinoma, also called penile mineral oil granuloma, occur after injection into the penis of foreign bodies such as mineral or vegetable oils. Clinical case: We present the case of a 29 years old male Gypsy patient who was consulted for nodules and fistulas on his penis. History revealed self-injection of kanamycin ointment into the penis body one year ago for the purpose of increasing the penile size. The diagnosis of penile paraffinoma was made. Circumcision with removal of nodules was performed. Histopathological examination by hematoxylin and eosin staining revealed the replacement of subcutaneous tissue with vacuolar lesions and a lymphocytic infiltrate with foreign-body giant cells. Discussion: Mineral or vegetable oils injection into the penis or other skin areas can be followed after a period of several years by the appearance of foreign body reactions with lipogranulomas formation. Other complications such as infection, skin necrosis, ulceration, fistulization, invasion of corpus cavernosum, embolism and even death may occur. Conclusion: The practice of injecting mineral and vegetable oils into the penile body, although abandoned in European countries, can be found in certain parts of the world and in certain social environments.