Fulminant Hepatic Failure as an Onset of Secondary Hemophagocytic Lymphohistiocytosis in Child - Case Report

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal syndrome that occurs as a consequence of pathological activation of the body's immune system which further generates a severe inflammatory response. Because HLH's clinical framework can be varied and because HLH is a rare disease, diagnosing it can prove to be quite challenging. We will present the clinical case of a child known with Nephrotic Syndrome, corticosteroid-dependent, who develops HLH, secondary to an Epstein Barr viral infection, with an onset that presents itself as a fulminant hepatic failure.