Could Knowledge of H. Pylory Pathogenicity Factors Lead to the Emergence of new Methods for Identifying Bacteria?

Abstract

H. pylori is an extracellular bacterial pathogen adapted to colonizing the gastric mucosa. It is currently recognized as the most common etiological factor involved in the genesis of digestive disorders with localization in the gastric mucosa, present in two-thirds of the world population in relation to socio-economic status. The relationship between the H. pylori bacteria and the human host can be explained in three stages, each involving specific factors. In the first stage H. pylori crosses the stomach and enters the gastric mucosa. The next step of joining the gastric epithelium and colonization of the mucosa leads to long-term resistance to treatment and chronic infection and it is facilitated by the genotypic and phenotypic diversity of H. pylori. In the third stage, we can observe the harmful action on the gastric mucosa.