Pseudomonas Aeruginosa in the Etiology of Paediatric Healthcare-Associated Infections

Authors

  • P.C. Chiriac University of Medicine and Pharmacy, Craiova, Romania
  • V. Poroch “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania
  • A.M. Pascu Transilvania University of Brasov, Romania
  • M. Hogea Transilvania University of Brasov, Romania
  • V. Carlig

Keywords:

healthcare-associated infections, Pseudomonas aeruginosa, antibiotic resistance, paediatrics

Abstract

Antimicrobial resistance is a global burden and crisis but also a significant threat to public health. The study's aim was to evaluate descriptively a group of pediatric patients with healthcare-associated infections with Pseudomonas aeruginosa, highlighting the strain's antibiotic resistance. Material and methods: the study was conducted on a group of 28 patients admitted to „Sf. Maria” Clinical Emergency Hospital for Children, Iasi. Result: most of the infections were diagnosed in infants (0-12 months) (42.85%), males (M/F ratio = 1.54), admitted to the acute therapy unit and intensive care unit, with the predominance of ventilator-associated pneumonia (31.74 %). The antibiotic resistance of P. aeruginosa strains was noted for Imipenem (50.00%) and Meropenem (46.42%), as well as Cefepime (42.85%) and Ceftazidime (28.57%). Only 12 isolates were tested for Piperacillin-Tazobactam (17.85% of them being resistant). Conclusions: antibiotic resistance of isolated strains had important levels of antibiotic resistance to Imipenem and Meropenem.

Author Biographies

P.C. Chiriac, University of Medicine and Pharmacy, Craiova, Romania

Department of Pharmacology

V. Poroch, “Grigore T. Popa” University of Medicine and Pharmacy, Iasi, Romania

Department of Surgery; 
Regional Institute of Oncology, Iasi, Romania

A.M. Pascu, Transilvania University of Brasov, Romania

Faculty of Medicine

M. Hogea, Transilvania University of Brasov, Romania

Faculty of Medicine

V. Carlig

Faculty of Medicine

Downloads

Published

2018-08-30

Issue

Section

MEDICAL SCIENCES