Polymorph Lymphoproliferation B and Common Variable Immunodeficiency 2 “TACI Mutation” in a 13 Years Boy – Case Report

Abstract

Common variable immunodeficiency (CVID) is one of the most frequent types of primary immunodeficiency that manifest a great variability in symptoms and severity. We present a case of a 13 years old boy initially diagnosed with primary cellular immune deficiency ( persistent lymphopenia) at the age of 3 years with repeated infections (staphylococcal infections, , herpes keratitis, onychomycosis, respiratory and digestive infections), afterward establishing the diagnosis of B polymorphic lymphoproliferation and common variable immunodeficiency 2 - TACI mutation, which for he is transferred to a clinic in Rome, Italy, in order to establish therapeutic conduct.