Ketonic Mannich Bases from Ortho- Hydroxyacetophenone, Ortho-Hydroxypropiophenone and Corresponding Oximes

Authors

  • I. Manciulea Transilvania University of Brasov, Romania
  • E. Comanita Gheorghe Asachi Technical University of Iasi, Romania
  • L. Dumitrescu Gheorghe Asachi Technical University of Iasi, Romania

Keywords:

Mannich bases, oximes, aminomethylation, Mannich reactions

Abstract

The paper presents the synthesis of a series of Mannich bases hydrochloride obtained from ortho-hydroxyacetophenone, orthohydroxypropiophenone, paraformaldehyde and some secondary amines hydrochlorides in 2-propanol. The obtained Mannich bases hydrochloride were transformed into oximes by treatment with hydroxylamine hydrochloride in aqueous sodium hydroxide. The separation of oximes from their sodium salts involved addition of acetic acid. The structure of compounds is confirmed by IR spectra.

Author Biographies

I. Manciulea, Transilvania University of Brasov, Romania

Centre “Product Design for Sustainable Development”

E. Comanita, Gheorghe Asachi Technical University of Iasi, Romania

Natural and Synthetic Polymers Dept.

L. Dumitrescu, Gheorghe Asachi Technical University of Iasi, Romania

Natural and Synthetic Polymers Dept.

Published

2008-12-17

Issue

Vol. 1(50)(2008)

Section

MATERIALS SCIENCE AND ENGINEERING